Linebacker Demetrius Flannigan-Fowles remains questionable due to a knee injury but could still make an appearance.
Who's out?
The 49ers will release their official inactive list 90 minutes before kickoff, but several players have already been ruled out. Some were declared unavailable on Friday, while others were more recent developments.
- G Aaron Banks
- DE Nick Bosa
- LB Dre Greenlaw
- RB Jordan Mason
- S George Odum
- T Trent Williams
Linebacker Dre Greenlaw remains on the physically unable to perform (PUP) list but is expected to return soon, potentially for Thursday night's game against the Los Angeles Rams.
On Saturday, the 49ers placed running back Jordan Mason on injured reserve due to a high-ankle sprain sustained against the Buffalo Bills, likely sidelining him for the remainder of the regular season. Surprisingly, safety George Odum landed on injured reserve with a knee injury that emerged late in the week.
The most significant absence on offense is left tackle Trent Williams, who will miss his third consecutive game as he continues to recover from an ankle injury. It's unclear if Williams will play again this season.
"Trent's really trying to get back out here," head coach Kyle Shanahan said last week. "It's just his ankle isn't healing the way we want. We can't get the swelling down and stuff."
On defense, the 49ers officially downgraded defensive end Nick Bosa on Saturday, ruling him out. Initially listed as doubtful due to hip and oblique injuries, this will mark his third missed game in a row.
Finally, left guard Aaron Banks has not cleared concussion protocol and will miss his second consecutive game. On Saturday, the 49ers downgraded him from questionable to out.
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