The 49ers have won their last five games, and now they'll take on the Seahawks in Week 18. Here's a look at the betting odds for the matchup.
49ers open as slight favorites in pivotal Week 18 matchup vs. Seahawks
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49ers open as slight favorites in Week 18 showdown with Seahawks
By David Bonilla
Dec 29, 2025
There's plenty at stake Saturday night when the San Francisco 49ers host the Seattle Seahawks at Levi's Stadium. The winner not only claims the NFC West crown but also secures the No. 1 seed in the NFC playoffs and home-field advantage.
For the 49ers, that top seed would be...
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