49ers vs. Colts recap: Brock Purdy explodes for five TDs in 48-27 win

What to Know The San Francisco 49ers (11-4) thumped the Indianapolis Colts (8-7) with a 48-27 victory on “Monday Night Football” in Week 16 at Lucas Oil Stadium. Brock Purdy dazzled in the team’s fifth straight win, completing 25 of his 34 pass attempts for 295 yards with a career-high five touchdowns, one interception and a 126.8 passer rating. Before exiting in the third quarter with an ankle injury, tight end George Kittle caught seven passes for 115 yards and a touchdown, while wide receiver Jauan Jennings hauled in five catches for 71 yards and a score of his own. Running back Christian McCaffrey surpassed the 1,000-yard rushing mark in the win, carrying 21 attempts for 117 yards and adding 29 receiving yards with two touchdowns on six catches. Read below for all the game highlights, news, analysis and postgame press conferences from Lucas Oil Stadium in Indianapolis: