Baker Mayfield delivered early fourth-quarter heroics to lead the Buccaneers past the 49ers, 30-19, improving Tampa Bay to 5-1. Mayfield threw two touchdown passes and extended a key drive with a spectacular third-and-14 scramble, setting up a 45-yard strike to rookie Tez Johnson for the clinching score. San Francisco, already banged up, lost star linebacker Fred Warner to a season-ending ankle injury, while Mac Jones threw for 347 yards but was picked off twice in the loss.
NFL Week 6 Recap: Tampa Bay Buccaneers 30, San Francisco 49ers 19
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Recap: 49ers lose much more than a game in 30-19 defeat to Buccaneers
By Kirk Larrabee
Oct 12, 2025
The shorthanded San Francisco 49ers put up a fight for much of the afternoon against the Buccaneers at Raymond James Stadium in Tampa on Sunday, but mistakes and missed opportunities down the stretch led to their leaving Tampa Bay with their second loss of the season -- a...
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