The San Francisco 49ers have dealt with plenty of offensive injuries this year, but the defense is taking several hits in Week 3.
49ers’ starting cornerback suffers injury in third quarter vs. Cardinals
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49ers vs. Cardinals injury updates: Bosa ruled out with knee injury
By David Bonilla
Sep 21, 2025
The San Francisco 49ers are facing the Arizona Cardinals at Levi's Stadium in Week 3. Below are the latest in-game injury updates for the 49ers. This article will be updated in real time as new information becomes available.
Players are listed in order of most recent...
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