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Nick Bosa injury update: 49ers DE ruled out of Week 3 game vs Cardinals with knee issue

Nick Bosa injury update: 49ers DE ruled out of Week 3 game vs Cardinals with knee issue

USA Today

Published Sep 21, 2025 at 2:20 PM

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Latest updates after Nick Bosa suffered a knee injury in the 49ers Week 3 game vs. Cardinals.

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49ers vs. Cardinals injury updates: Bosa ruled out with knee injury

49ers vs. Cardinals injury updates: Bosa ruled out with knee injury

By David Bonilla

Sep 21, 2025

The San Francisco 49ers are facing the Arizona Cardinals at Levi's Stadium in Week 3. Below are the latest in-game injury updates for the 49ers. This article will be updated in real time as new information becomes available. Players are listed in order of most recent...

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