The 49ers listed Jauan Jennings as questionable with a shoulder injury last week after he had one limited practice day. He played 62 of 71 offensive snaps and caught five passes for 89 yards and a touchdown.The team is hoping for the same this week as it again lists Jennings as questionable.Jennings, unlike last week, did not practice at all this week after injuring his ankle against the Saints.It is more concerning this week with wide receiver Jordan Watkins (calf) already ruled out. The 49ers added Watkins to the injury report on Thursday after limited work, and he did not practice Friday.The 49ers also ruled out offensive tackle Spencer Burford (knee).Offensive guard Connor Colby (groin) and quarterback Brock Purdy (left shoulder/toe) are questionable. Coach Kyle Shanahan said it is "highly unlikely" that Purdy plays.Colby was a new addition to the injury report on Friday.
49ers WR Jauan Jennings is questionable to play vs. Cardinals
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49ers vs. Cardinals final injury report: Purdy, Jennings, Colby questionable for Week 3
By David Bonilla
Sep 19, 2025
The San Francisco 49ers are preparing for their Week 3 contest against the Arizona Cardinals on Sunday at Levi's Stadium in Santa Clara, California. Both teams have released their official injury reports, which are provided below.
San Francisco 49ers
Out
T Spencer Burford...
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