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• Notable injuries, news from Sunday's Week 3 games: 49ers DE Nick Bosa (knee) ruled out vs. Cardinals
  From the Web › NFL.com
  Here are the injuries and news we're monitoring around the league on this Week 3 Sunday.
  Share • Sep 21, 2025 at 2:20 PM
• 49ers vs. Cardinals injury updates: Bosa ruled out with knee injury
  49ers Webzone › Articles
  49ers vs. Cardinals Week 3 injury updates: Nick Bosa exits with a knee injury. Follow real-time reports on key player statuses from Levi's Stadium.
  David Bonilla • Share • Sep 21, 2025 at 2:10 PM
• NFL Week 3 takeaways: What We Learned from Sunday's 14 games
  From the Web › NFL.com
  Around The NFL breaks down what you need to know from Sunday's action in Week 3 of the 2025 NFL season.
  Share • Sep 21, 2025 at 1:40 PM
• Brock Purdy, Jauan Jennings, Paris Johnson all inactive for 49ers-Cardinals
  From the Web › Pro Football Talk
  Mac Jones is officially getting his second start for the 49ers. San Francisco and Arizona each have key starters inactive for Sunday's NFC West matchup, as Brock Purdy...
  Share • Sep 21, 2025 at 12:21 PM
• QB Brock Purdy leads list of 49ers' inactives vs. Cardinals in Week 3
  From the Web › Niners Wire
  The San Francisco 49ers and Arizona Cardinals are set to kick off on Sunday, and they'll be without a few players, who have been deemed inactive.
  Share • Sep 21, 2025 at 12:00 PM
• Brock Purdy, Jauan Jennings OUT vs. Cardinals; Inactives for Week 3 #AZvsSF
  From the Web › 49ers.com
  Take a look at players who have been ruled out for the San Francisco 49ers Week 3 matchup versus the Arizona Cardinals.
  Share • Sep 21, 2025 at 12:00 PM
• Purdy, Jennings among 6 49ers players inactive vs. Cardinals; Colby active
  49ers Webzone › Articles
  49ers' Brock Purdy and Jauan Jennings headline six inactives vs. Cardinals, while rookie guard Connor Colby suits up in Week 3 matchup.
  David Bonilla • Share • Sep 21, 2025 at 11:57 AM
• 60K club: Aaron Rodgers jumps to sixth all time, Matthew Stafford eyes ninth
  From the Web › ESPN
  Matthew Stafford needed 191 yards coming into Week 1 to join the prestigious quarterback club.
  Share • Sep 21, 2025 at 11:00 AM
• 49ers vs. Cardinals highlights: San Francisco wins sloppy NFL Week 3 game
  From the Web › Niners Wire
  The San Francisco 49ers struggled in their home opener, but they left Week 3 with a win vs. the Arizona Cardinals. Here are the highlights.
  Share • Sep 21, 2025 at 10:40 AM
• How 'safety blanket' Christian McCaffrey comforts 49ers QB Mac Jones in huddle
  From the Web › NBCS Bay Area
  What to Know The 49ers improved to 3-0 on the 2025 NFL season after a 16-15 win over the Arizona Cardinals on Sunday at Levi’s Stadium Mac Jones made his second...
  Share • Sep 21, 2025 at 10:40 AM
• 49ers deliver devastating injury update before Week 3 matchup vs. Cardinals
  From the Web › Niners Wire
  The San Francisco 49ers will be down another offensive starter Sunday when they host the Arizona Cardinals.
  Share • Sep 21, 2025 at 10:20 AM
• 49ers WR Jauan Jennings reportedly will miss Week 3 vs. Cardinals
  From the Web › SFGate
  The 49ers lose yet another starter on offense.
  Share • Sep 21, 2025 at 10:00 AM
• 49ers-Cardinals live updates: Niners win defensive duel despite Bosa injury
  From the Web › The Mercury News
  Jauan Jennings will join Brock Purdy on the 49ers' sideline and not play in today's home opener against the Arizona Cardinals
  Share • Sep 21, 2025 at 9:40 AM
  May require subscription
• Jennings out for injury-plagued Niners vs. Cards
  From the Web › ESPN
  Share • Sep 21, 2025 at 9:20 AM
• Report: Jauan Jennings will not play against the Cardinals
  From the Web › Pro Football Talk
  The 49ers are set to be without both quarterback Brock Purdy and wide receiver Jauan Jennings for Sunday's game against the Cardinals. Adam Schefter of ESPN reports that...
  Share • Sep 21, 2025 at 9:20 AM
• How Jauan Jennings' absence will affect the 49ers against the Cardinals
  From the Web › SI.com
  The 49ers won't have their No. 1 wide receiver this afternoon when they face the Arizona Cardinals. That's because Jauan Jennings has been ruled out for Week 3 with...
  Share • Sep 21, 2025 at 9:20 AM
• NFL Week 3 inactives: Players ruled out for Sunday's 14 games
  From the Web › NFL.com
  NFL.com keeps you up to date with the inactive reports for every Sunday game in Week 3 of the 2025 NFL season.
  Share • Sep 21, 2025 at 9:00 AM
• Injured 49ers QB Brock Purdy reportedly beating initial timeline
  From the Web › SFGate
  Purdy isn't starting for the Week 3 showdown with the Cardinals.
  Share • Sep 21, 2025 at 8:40 AM
• 49ers deliver tough injury news: Jauan Jennings, Brock Purdy out vs. Cardinals
  49ers Webzone › Articles
  49ers QB Mac Jones faces Cardinals without WR Jauan Jennings and Brock Purdy, both sidelined by injuries in this key NFC West matchup.
  David Bonilla • Share • Sep 21, 2025 at 8:32 AM
• NFL Week 3 injuries to monitor for Sunday's games: Buccaneers WR Emeka Egbuka (hip/groin) expected to play without limitations vs. Jets
  From the Web › NFL.com
  NFL.com keeps you up to date with all of the latest injury updates ahead of Sunday's games.
  Share • Sep 21, 2025 at 8:20 AM
• Rapoport: 49ers' Brock Purdy could return as starter in Week 4
  49ers Webzone › Articles
  49ers QB Brock Purdy is recovering from his toe injury and could return to the starting lineup for Week 4. Mac Jones will start today against the Cardinals.
  David Bonilla • Share • Sep 21, 2025 at 7:27 AM
• Will Jauan Jennings play in Week 3 for the 49ers?
  From the Web › For The Win
  What's the latest on Jauan Jennings' injury? Here's what we know.
  Share • Sep 21, 2025 at 5:20 AM
• Backup QBs take center stage with five making starts in Week 3, including Bengals' Jake Browning
  From the Web › NFL.com
  NFL Network Insider Ian Rapoport takes a look at the situations involving five backup QBs who are making starts in the NFL in Week 3, leading with the Cincinnati...
  Share • Sep 21, 2025 at 2:00 AM
• Jauan Jennings injury update: Will 49ers WR play vs. Cardinals?
  From the Web › Niners Wire
  San Francisco 49ers wide receiver Jauan Jennings is questionable to suit up in Week 3 vs. the Arizona Cardinals. Here's the latest on his injuries.
  Share • Sep 20, 2025 at 9:20 PM
• Fantasy Football start/sit recommendations for the 49ers in Week 3 vs. Cardinals
  From the Web › Niners Wire
  The San Francisco 49ers and Arizona Cardinals will meet on Sunday. Here's what fantasy owners should do with their 49ers in Week 3.
  Share • Sep 20, 2025 at 5:20 PM
• 49ers elevate QB Adrian Martinez, WR Malik Turner
  From the Web › Pro Football Talk
  The 49ers elevated quarterback Adrian Martinez from the practice squad for Sunday's game against the Cardinals, the team announced.With Mac Jones expected to start for a...
  Share • Sep 20, 2025 at 2:20 PM
• What 49ers roster moves mean for Brock Purdy, Jauan Jennings injuries
  From the Web › Niners Wire
  The San Francisco 49ers are adding a third QB to their roster for the second week in a row as Brock Purdy deals with a toe injury.
  Share • Sep 20, 2025 at 2:00 PM
• 49ers elevate two players, place Spencer Burford on IR ahead of home opener against Cardinals
  49ers Webzone › Articles
  49ers place Spencer Burford on IR, elevate QB Adrian Martinez and WR Malik Turner ahead of home opener vs. Cardinals at Levi's Stadium.
  Marc Adams • Share • Sep 20, 2025 at 1:50 PM
• 49ers place Spencer Burford on IR, elevate QB Adrian Martinez to face Cardinals
  From the Web › NBCS Bay Area
  The 49ers on Saturday elevated quarterback Adrian Martinez and wide receiver Malik Turner from the practice squad to be available to play Sunday against the Arizona...
  Share • Sep 20, 2025 at 1:40 PM
• 49ers Place OL Spencer Burford on IR, Other Moves Ahead of #AZvsSF
  From the Web › 49ers.com
  The San Francisco 49ers today announced a series of roster moves ahead of the Week 3 contest.
  Share • Sep 20, 2025 at 1:40 PM
• How One Rookie Singlehandedly Fixed the 49ers' Run Defense
  From the Web › SI.com
  Through two games, Mykel Williams has been one of the most valuable and impactful players on the team, and yet has recorded just six tackles.
  Share • Sep 20, 2025 at 1:00 PM
• 5 Bold 49ers Predictions vs. Cardinals in Week 3 Including Final Score
  From the Web › SI.com
  Two of the most injured teams in the league will face each other on Sunday when the 49ers host the Cardinals at Levi's Stadium.
  Share • Sep 20, 2025 at 10:57 AM
• Kyle Shanahan discusses how 49ers defense will approach slowing down Cardinals QB Kyler Murray
  49ers Webzone › Articles
  49ers' Kyle Shanahan reveals how San Francisco's defense plans to contain Cardinals QB Kyler Murray in their NFC West showdown.
  Marc Adams • Share • Sep 20, 2025 at 10:31 AM
• Kurtenbach: Can Mac Jones keep it up? Three predictions for 49ers-Cardinals
  From the Web › The Mercury News
  A battle of 2-0 teams will put the winner in the drivers' seat in the NFC West.
  Share • Sep 20, 2025 at 10:00 AM
  May require subscription
• 49ers' Kyle Shanahan very encouraged by progress of QB Brock Purdy's toe injury
  49ers Webzone › Articles
  Kyle Shanahan says he's "very encouraged" by Brock Purdy's turf toe recovery as the 49ers QB inches closer to returning after injury.
  Marc Adams • Share • Sep 20, 2025 at 9:45 AM
• 49ers vs. Cardinals: 4 things to know heading into the Week 3 matchup
  From the Web › Niners Wire
  The San Francisco 49ers and Arizona Cardinals will meet on Sunday for an NFC West battle in Week 3. Here's what fans should know before the game.
  Share • Sep 20, 2025 at 9:40 AM
• 49ers vs. Cardinals: Injury updates, predictions from 49ers Week 3 opponent
  From the Web › Niners Wire
  The San Francisco 49ers have had a tough time with the Arizona Cardinals since head coach Kyle Shanahan took over in the 2017 season.
  Share • Sep 20, 2025 at 9:00 AM
• Why are the 49ers wearing white jerseys at home vs. the Cardinals?
  49ers Webzone › Articles
  The 49ers will wear white jerseys at home vs. the Cardinals. Head coach Kyle Shanahan explains the strategic reason is to beat the heat.
  David Bonilla • Share • Sep 20, 2025 at 9:00 AM
• All announced players have received permission for Saudi Arabia flag football tournament
  From the Web › Pro Football Talk
  In a memo sent on Friday, the NFL informed all teams that it is within their "exclusive discretion" to determine whether players who would like to participate...
  Share • Sep 20, 2025 at 8:00 AM
• 49ers vs. Cardinals: 3 Keys to Victory in a Week 3 NFC West Showdown
  49ers Webzone › Editorials
  49ers vs. Cardinals Week 3 preview: Key matchups, strategies, and what San Francisco must do to stay undefeated and take control of the NFC West.
  Wayne "Breezie" Brown • Share • Sep 20, 2025 at 8:00 AM
• Five starting quarterbacks won't start this weekend, due to injury
  From the Web › Pro Football Talk
  Quarterback remains, by far, the most important position on any NFL team. On Sunday, five of the 28 teams that will be playing won't have their best quarterback under...
  Share • Sep 20, 2025 at 7:20 AM
• 49ers' 5 keys to winning home opener against Arizona Cardinals
  From the Web › The Mercury News
  SANTA CLARA – All-white throwback jerseys are to serve as the 49ers' heat shield if Sunday's home opener with Arizona turns into another scorching showdown like...
  Share • Sep 20, 2025 at 5:40 AM
  May require subscription
• Unpacking the 49ers bizarre QB situation heading into Week 3
  From the Web › Niners Wire
  The San Francisco 49ers could completely flip their QB depth chart with Brock Purdy working through a toe injury.
  Share • Sep 20, 2025 at 5:20 AM
• Alleged Ricky Pearsall shooter won't be tried as an adult
  From the Web › Pro Football Talk
  A judge ruled on Friday that the teenager who allegedly shot 49ers receiver Ricky Pearsall in September 2024 will be tried as a juvenile.The suspect was 17 at the time...
  Share • Sep 20, 2025 at 5:00 AM
• Teen charged in shooting of 49ers WR Ricky Pearsall will not be tried as adult
  From the Web › NFL.com
  The teen charged with shooting San Francisco 49ers wide receiver Ricky Pearsall during an attempted robbery last year will be tried as a juvenile, a judge ruled...
  Share • Sep 19, 2025 at 8:20 PM
• More 49ers added: George Kittle and Fred Warner to join flag football tournament in Saudi Arabia
  49ers Webzone › Articles
  More 49ers stars are headed to Saudi Arabia. George Kittle and Fred Warner will join Christian McCaffrey for a celebrity flag football tournament.
  David Bonilla • Share • Sep 19, 2025 at 8:09 PM
• 49ers may already have to replace their newest starting offensive lineman
  From the Web › Niners Wire
  The San Francisco 49ers may have to dig deep into their depth chart to find a starting left guard alongside Trent Williams in Week 3.
  Share • Sep 19, 2025 at 8:00 PM
• The 49ers' 'six layers' of QB maneuvers ahead of matchup with Cardinals
  From the Web › San Francisco Standard
  As Kyle Shanahan figures out Brock Purdy's status for Sunday, Jed York welcomes Roger Goodell to San Francisco to kick off Super Bowl LX festivities.
  Share • Sep 19, 2025 at 5:00 PM
  May require subscription
• Judge rules teen suspected of shooting 49ers' Ricky Pearsall won't be tried as an adult
  49ers Webzone › Articles
  A judge has ruled that the teen accused of shooting 49ers WR Ricky Pearsall will be tried as a juvenile, avoiding a potential life sentence.
  David Bonilla • Share • Sep 19, 2025 at 4:42 PM
• Transcript: Kyle Shanahan shares final updates ahead of 49ers-Cardinals Week 3 matchup
  49ers Webzone › Articles
  San Francisco 49ers head coach Kyle Shanahan spoke to reporters following Friday's practice, providing final updates ahead of the team's Week 3 matchup against the...
  Site Staff • Share • Sep 19, 2025 at 3:26 PM
• 49ers to start Jones at QB in place of ailing Purdy
  From the Web › ESPN
  Barring a significant last-minute change, the San Francisco 49ers will start Mac Jones at quarterback for a second consecutive week Sunday against the Arizona...
  Share • Sep 19, 2025 at 3:20 PM
• Purdy, Jennings, Colby Questionable for Week 3; Injury Report Ahead of #AZvsSF
  From the Web › 49ers.com
  The San Francisco 49ers released their latest injury updates headed into the Week 3 contest versus the Arizona Cardinals.
  Share • Sep 19, 2025 at 3:20 PM
• 49ers deliver unfortunate injury news on Connor Colby, Jordan Watkins, Spencer Burford
  49ers Webzone › Articles
  The San Francisco 49ers are dealing with a wave of injuries. Get the latest on Brock Purdy, Connor Colby, Jordan Watkins, and Spencer Burford.
  David Bonilla • Share • Sep 19, 2025 at 3:07 PM
• Cardinals don't expect CB Will Johnson to play Sunday
  From the Web › Pro Football Talk
  The Cardinals are set to be thin at cornerback for Sunday's game against the 49ers. Second-round pick Will Johnson is listed as doubtful after missing practice all week...
  Share • Sep 19, 2025 at 3:00 PM
• Kyle Shanahan: Brock Purdy is "highly unlikely" to start on Sunday
  From the Web › Pro Football Talk
  It was wise for quarterback Brock Purdy to get his long-term deal before the 2025 season began.Purdy will likely miss his second straight game since suffering toe and...
  Share • Sep 19, 2025 at 3:00 PM
• 49ers WR Jauan Jennings is questionable to play vs. Cardinals
  From the Web › Pro Football Talk
  The 49ers listed Jauan Jennings as questionable with a shoulder injury last week after he had one limited practice day. He played 62 of 71 offensive snaps and caught...
  Share • Sep 19, 2025 at 3:00 PM
• Kyle Shanahan's latest update on Brock Purdy's status for Week 3 isn't promising
  From the Web › Niners Wire
  The San Francisco 49ers may not have their starting quarterback again in Week 3 vs. the Arizona Cardinals.
  Share • Sep 19, 2025 at 2:40 PM
• Brock Purdy, Jauan Jennings questionable for 49ers' Week 3 game vs. Cardinals
  From the Web › NBCS Bay Area
  Programming note: Watch Matt Maiocco’s full interview with Kyle Shanahan on “49ers Game Plan,” airing at 9 p.m. PT Friday on NBC Sports Bay...
  Share • Sep 19, 2025 at 2:40 PM
• Teen in Pearsall shooting won't be tried as adult
  From the Web › ESPN
  The teen charged with shooting San Francisco 49ers wide receiver Ricky Pearsall during an attempted robbery last year will be tried as a juvenile, a judge ruled...
  Share • Sep 19, 2025 at 2:40 PM
• Niners QB Brock Purdy (shoulder/toe; questionable) unlikely to serve as starter Sunday vs. Cardinals
  From the Web › NFL.com
  San Francisco 49ers quarterback Brock Purdy is officially questionable for San Francisco's Week 3 game against the Arizona Cardinals but is "highly...
  Share • Sep 19, 2025 at 2:40 PM