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• 49ers vs. Rams injury updates: Several key players ailing in NFC West battle
  49ers Webzone › Articles
  San Francisco 49ers injury updates from the Thursday Night Football matchup against the Los Angeles Rams at SoFi Stadium.
  David Bonilla • Share • Oct 2, 2025 at 6:07 PM
• Rams-49ers NFL Week 5: Niners pull out win over Rams 26-23
  From the Web › ESPN
  Share • Oct 2, 2025 at 5:40 PM
• Mac Jones has 49ers out to 7-0 lead
  From the Web › Pro Football Talk
  Brock who?Mac Jones, who is starting for the third time this season in the absence of Brock Purdy, drove the 49ers right down the field after the opening kickoff. The...
  Share • Oct 2, 2025 at 5:40 PM
• Report: Brock Purdy could miss next week's game, too
  From the Web › Pro Football Talk
  The 49ers are playing another game without Brock Purdy, with Mac Jones starting Thursday Night Football against the Rams. It is the third game Jones has started this...
  Share • Oct 2, 2025 at 5:20 PM
• 49ers QB Brock Purdy's injury 'setback' could keep him out multiple games again
  From the Web › SFGate
  Brock Purdy might be back later than expected.
  Share • Oct 2, 2025 at 5:20 PM
• Wyche and Jeremiah break down what to expect from 49ers-Rams rivalry in 'TNF' | 'NFL Gameday Kickoff'
  From the Web › NFL.com
  Chief National Reporter Steve Wyche and NFL Network analyst Daniel Jeremiah discuss what to expect in Week 5 matchup between the San Francisco 49ers and Los Angeles Rams...
  Share • Oct 2, 2025 at 5:04 PM
• Three Storylines for Thursday Night Football: Can Puka Nacua Continue Historic Season?
  From the Web › Touchdown Wire
  Heading into a pivotal divisional match-up on Thursday Night Football, can a hamstrung Niners team keep up with Puka Nacua and the Rams?
  Share • Oct 2, 2025 at 5:00 PM
• Niners QB Brock Purdy week to week with toe injury, could miss more time
  From the Web › NFL.com
  Brock Purdy is considered week to week and has no timetable for his return from a toe injury that has him inactive for the San Francisco 49ers’ Week 5 game...
  Share • Oct 2, 2025 at 5:00 PM
• Rapoport: 49ers QB Brock Purdy could miss Buccaneers game too
  49ers Webzone › Articles
  After a setback with his turf toe, 49ers QB Brock Purdy is week-to-week and could miss the Buccaneers game, per Ian Rapoport. Mac Jones starts tonight.
  David Bonilla • Share • Oct 2, 2025 at 4:59 PM
• Thursday Night Football: TE Tyler Higbee, RT Rob Havenstein are inactive vs. 49ers
  From the Web › Pro Football Talk
  The Rams listed tight end Tyler Higbee (hip) and right tackle Rob Havenstein (ankle) as doubtful for Thursday Night Football. As expected, they will...
  Share • Oct 2, 2025 at 4:40 PM
• Best of NFL Week 5's arrivals, featuring Patrick Mahomes
  From the Web › ESPN
  Share • Oct 2, 2025 at 4:20 PM
• No surprises in star-studded 49ers list of inactives for Week 5 game vs. Rams
  From the Web › Niners Wire
  The San Francisco 49ers injury problems shined through in their list of inactive players for their Week 5 matchup vs. the Rams.
  Share • Oct 2, 2025 at 4:00 PM
• 49ers vs. Rams highlights: San Francisco pulls out miracle win in NFL Week 5 game
  From the Web › Niners Wire
  The San Francisco 49ers stayed atop the NFC West with a miracle win over the Los Angeles Rams in Week 5. Here are the highlights.
  Share • Oct 2, 2025 at 4:00 PM
• Niners vs. Rams Week 5 inactives: Players ruled out for Thursday's game
  From the Web › NFL.com
  The official inactives for Week 5 "Thursday Night Football": San Francisco 49ers at Los Angeles Rams.
  Share • Oct 2, 2025 at 4:00 PM
• Jones Set to Start TNF; Pearsall, Jennings OUT; Inactives for Week 5 #SFvsLAR
  From the Web › 49ers.com
  Take a look at players who have been ruled out for the San Francisco 49ers Week 5 "Thursday Night Football" matchup versus the Los Angeles Rams.
  Share • Oct 2, 2025 at 4:00 PM
• These 7 49ers players are inactive vs. Rams
  49ers Webzone › Articles
  49ers rule Brock Purdy, Ricky Pearsall and 5 others inactive vs. Rams; Adrian Martinez promoted as backup for Thursday Night Football showdown.
  David Bonilla • Share • Oct 2, 2025 at 3:47 PM
• 49ers injuries ahead of 'TNF' matchup vs. the Rams | 'The Insiders'
  From the Web › NFL.com
  NFL media insider Tom Pelissero reports San Francisco 49ers quarterback Brock Purdy, wide receiver Jauan Jennings and wide receiver Ricky Pearsall all ruled out on 'The...
  Share • Oct 2, 2025 at 3:29 PM
• 49ers vs. Rams recap: Mac Jones delivers in incredible 26-23 OT win
  From the Web › NBCS Bay Area
  What to Know Programming note: Immediately after the Week 16 game ends, watch “49ers Postgame Live” on NBC Sports Bay Area or stream the show in the NBC...
  Share • Oct 2, 2025 at 3:20 PM
• 49ers injury wave sparks massive ticket price drop ahead of Rams game
  From the Web › SFGate
  49ers fans were expected to make up the majority of the crowd for Thursday's game.
  Share • Oct 2, 2025 at 2:20 PM
• Does 49ers' latest roster move hint at an extended Brock Purdy absence?
  49ers Webzone › Articles
  Is Brock Purdy's turf toe more serious? The 49ers signed QB Adrian Martinez to the active roster, suggesting Purdy's return status is now uncertain.
  David Bonilla • Share • Oct 2, 2025 at 2:17 PM
• 49ers flurry of Week 5 roster moves could be bad news long-term for Brock Purdy
  From the Web › Niners Wire
  The San Francisco 49ers added a third quarterback to their active roster, which may portend bad news for QB Brock Purdy.
  Share • Oct 2, 2025 at 1:40 PM
• 49ers sign QB Adrian Martinez to active roster
  From the Web › Pro Football Talk
  The 49ers elevated quarterback Adrian Martinez from the practice squad on a temporary basis when Brock Purdy missed a couple of games earlier this year, but they made a...
  Share • Oct 2, 2025 at 1:40 PM
• 49ers promote QB Adrian Martinez, elevate receiver Malik Turner to face Rams
  From the Web › NBCS Bay Area
  The 49ers on Thursday promoted No. 3 quarterback Adrian Martinez to a spot on the team’s 53-man roster.Martinez will serve as the backup quarterback when the 49ers...
  Share • Oct 2, 2025 at 1:20 PM
• 49ers Promote QB Martinez to Active Roster, Other Moves Ahead of #SFvsLAR
  From the Web › 49ers.com
  The San Francisco 49ers have announced the following roster moves ahead of "Thursday Night Football."
  Share • Oct 2, 2025 at 1:20 PM
• 49ers announce key roster moves ahead of TNF showdown with Rams
  49ers Webzone › Articles
  49ers shake up roster before TNF vs. Rams: Brock Purdy out, Mac Jones starting, Adrian Martinez promoted, and key WRs sidelined.
  Site Staff • Share • Oct 2, 2025 at 1:08 PM
• These Brock Purdy stats will shock San Franicsco 49ers fans
  From the Web › SI.com
  Brock Purdy is in a bit of a slump. To be fair, he's also injured. He hurt his toe in Week 1, missed Weeks 2 and 3 and then reinjured his toe in Week 4. Now, it's...
  Share • Oct 2, 2025 at 1:00 PM
• What's the 49ers' biggest need heading into Week 5?
  49ers Webzone › Articles
  The injury-hit 49ers are without Purdy, Pearsall, and Jennings. CBS Sports argues wide receiver, not the Bosa-less pass rush, is their biggest crisis.
  David Bonilla • Share • Oct 2, 2025 at 12:25 PM
• NFL Week 5 Preview: Schedule, storylines, matchups to watch and betting spreads
  From the Web › Pro Football Focus
  We're diving into all 14 matchups in Week 5 of the 2025 NFL season â?? including key storylines, matchups to watch and injury news, starting with...
  Share • Oct 2, 2025 at 12:20 PM
• Puka Nacua needs eight catches tonight to make history
  From the Web › Pro Football Talk
  Rams receiver Puka Nacua is on a record pace. And he's one game away from doing something unprecedented.With eight catches tonight against the 49ers, Nacua will become...
  Share • Oct 2, 2025 at 12:00 PM
• Former 49ers TE, two-time Pro Bowler launches new podcast
  From the Web › Niners Wire
  Former San Francisco 49ers tight end Vernon Davis was one of the best tight ends in the game, and now he's on to podcasting.
  Share • Oct 2, 2025 at 11:00 AM
• George Kittle injury return: When will 49ers TE come back?
  From the Web › For The Win
  The 49ers miss their big tight end. Here's when we might see George Kittle again.
  Share • Oct 2, 2025 at 11:00 AM
• NFL QB rankings, Week 5: Patrick Mahomes, Dak Prescott shake up top 5; who sank 12 spots?
  From the Web › NFL.com
  Which player enters the top five in Nick Shook's QB Index rankings? Who falls 12 spots? Check out the updated pecking order, 1-32, heading into Week 5 of the 2025...
  Share • Oct 2, 2025 at 11:00 AM
• 49ers rookie Upton Stout earns high praise from ESPN's Bill Barnwell
  49ers Webzone › Articles
  49ers rookie Upton Stout shines in ESPN's quarter-season awards as a top Defensive Rookie of the Year pick, proving his impact early in 2025.
  David Bonilla • Share • Oct 2, 2025 at 10:53 AM
• NFL picks for every Week 5 game: 49ers vs. Rams TNF prediction unanimous
  From the Web › NFL.com
  Who takes tonight's NFC West showdown between the 49ers and Rams? Can Dillon Gabriel guide the Browns to a London win in his starting debut? Will the Broncos hand...
  Share • Oct 2, 2025 at 10:40 AM
• Christian McCaffrey is the third NFL player with 60 rushes, 30 catches through four games
  From the Web › Pro Football Talk
  49ers running back Christian McCaffrey is healthy again. And he's as effective as ever.He's the third player in league history with 60 or more rushing attempts and 30 or...
  Share • Oct 2, 2025 at 10:40 AM
• Which 49ers stars won't play against the Rams on Thursday night?
  49ers Webzone › Articles
  Key 49ers stars, including QB Brock Purdy and WRs Ricky Pearsall & Jauan Jennings, are out for the crucial Thursday Night Football clash against the Rams.
  David Bonilla • Share • Oct 2, 2025 at 10:26 AM
• Why isn't Nick Bosa playing Thursday night?
  From the Web › For The Win
  The 49ers are without one of their best players on Thursday night for a good reason.
  Share • Oct 2, 2025 at 10:00 AM
• 49ers legend Roger Craig among senior Pro Football Hall of Fame candidates
  From the Web › NBCS Bay Area
  Former 49ers running back Roger Craig, the inaugural member of the NFL’s 1,000/1,000 club, is among 52 remaining seniors candidates for the Pro Football Hall of...
  Share • Oct 2, 2025 at 9:40 AM
• 49ers vs. Rams: 5 Key Players to Watch in Week 5 Battle for NFC West Lead
  49ers Webzone › Editorials
  49ers and Rams clash for NFC West lead in Week 5. Here are 5 key players who could define the outcome of this primetime rivalry showdown.
  Casey Lima • Share • Oct 2, 2025 at 9:17 AM
• Rumors of fake crowd noise resurface ahead of 49ers-Rams in LA
  From the Web › SFGate
  A former 49ers player is throwing another accusation at the Rams.
  Share • Oct 2, 2025 at 9:00 AM
• NFL Week 5: Line moves and totals swings to know
  From the Web › Pro Football Focus
  Injuries, weather, and public pick releases are just a few factors that can swing numbers. But spotting early signalsâ??before prices settle into full...
  Share • Oct 2, 2025 at 8:40 AM
• RB Craig, QB Anderson advance in HOF process
  From the Web › ESPN
  Versatile running back Roger Craig, former MVP Ken Anderson and special teams standout Steve Tasker are among the 52 players who advanced to the next stage for the Pro...
  Share • Oct 2, 2025 at 8:40 AM
• 49ers Throwback: The Hated Rams
  49ers Webzone › Editorials
  49ers vs. Rams: A rivalry spanning 70+ years, filled with classic battles, playoff drama, and divisional showdowns. History meets Week 5 at SoFi.
  Sasha D. Robinson • Share • Oct 2, 2025 at 8:33 AM
• 49ers vs. Rams: Who did the experts pick for the NFC West showdown?
  From the Web › Niners Wire
  The San Francisco 49ers will take on the Los Angeles Rams tonight. Here's what the experts think will happen on Thursday at SoFi Stadium.
  Share • Oct 2, 2025 at 8:20 AM
• 2025 NFL defensive line rankings ahead of Week 4: The Cleveland Browns continue to dominate
  From the Web › Pro Football Focus
  The Browns' unit has earned a 90.5 overall grade, led by Myles Garrett at 92.9. Maliek Collins has been dominant on the interior with a 90.2 grade â?? seventh-best...
  Share • Oct 2, 2025 at 7:40 AM
• Fantasy Football start/sit recommendations for the 49ers in Week 5 vs. Rams
  From the Web › Niners Wire
  The San Francisco 49ers and Los Angeles Rams will meet at SoFi Stadium on Thursday. Here's what fantasy owners should do with their 49ers in Week 5.
  Share • Oct 2, 2025 at 6:40 AM
• 49ers vs. Rams: The Standard's 5 fast predictions
  From the Web › San Francisco Standard
  The Niners are short-handed on a short week. Does that guarantee they'll come up short?
  Share • Oct 2, 2025 at 6:20 AM
  May require subscription
• 49ers' 5 keys to upsetting the Rams at Levi's South in NFC West battle
  From the Web › The Mercury News
  The 49ers (3-1) must find a way to pressure the Rams' Matthew Stafford without Nick Bosa and also contain NFL-leading wide receiver Puka Nacua.
  Share • Oct 2, 2025 at 5:40 AM
  May require subscription
• Will Ricky Pearsall, Jauan Jennings play on Thursday night for 49ers?
  From the Web › For The Win
  What's the latest on Ricky Pearsall's and Jauan Jennings' injuries? Here's what we know.
  Share • Oct 2, 2025 at 4:40 AM
• 49ers-Rams injury report: Is Brock Purdy playing Thursday night?
  From the Web › For The Win
  Brock Purdy's status for Thursday night is up in the air. Looking at the 49ers vs. Rams injury report.
  Share • Oct 2, 2025 at 4:20 AM
• Thursday Night Football: San Francisco 49ers-Los Angeles Rams betting preview (odds, lines, best bets)
  From the Web › Pro Football Focus
  In a battle between division rivals, Los Angeles Rams RB Kyren Williams may gain an upper hand.
  Share • Oct 2, 2025 at 4:00 AM
• Barnwell's NFL quarter-season awards: The top candidates to win MVP, Rookie of the Year, more
  From the Web › ESPN
  Can Josh Allen win another MVP? Could anyone edge Myles Garrett for DPOY? We ranked the top three candidates to win seven NFL awards through four weeks.
  Share • Oct 2, 2025 at 3:40 AM
• When will Brandon Aiyuk return? 49ers WR injury update
  From the Web › USA Today
  49ers wide receiver Brandon Aiyuk has yet to play a snap in 2025. How long is Aiyuk out? When will he return?
  Share • Oct 2, 2025 at 3:20 AM
• When will George Kittle return? 49ers TE injury update
  From the Web › USA Today
  San Francisco 49ers tight end George Kittle has been on injured reserve since his Week 1 hamstring injury. When will he return?
  Share • Oct 2, 2025 at 3:20 AM
• How the 49ers are using the Rams' blueprint to rebuild around Brock Purdy
  From the Web › ESPN
  The 49ers started to plan Brock Purdy's extension in 2022 -- and their division rivals helped them.
  Share • Oct 2, 2025 at 3:20 AM
• Where shorthanded 49ers might have advantage vs. tough Rams team in Week 5
  From the Web › NBCS Bay Area
  The 49ers have a tough challenge ahead facing one of the most productive defensive lines in the NFL, but the Los Angeles Rams also will offer plenty of opportunities on...
  Share • Oct 1, 2025 at 9:20 PM
• Baldinger and Wyche break down 49ers vs. Rams 'TNF' matchup | 'The Insiders'
  From the Web › NFL.com
  NFL Network analyst Brian Baldinger and Chief National Reporter Steve Wyche discuss the impact of San Francisco 49ers injuries will have against the Los Angeles Rams...
  Share • Oct 1, 2025 at 7:20 PM
• Rams star jokes that he won't trash talk Trent Williams because he's 'not dumb'
  From the Web › Niners Wire
  San Francisco 49ers offensive lineman Trent Williams is still one of the scariest players in the league, even keeping Jared Verse from trash talking.
  Share • Oct 1, 2025 at 3:20 PM
• Brock Purdy, Ricky Pearsall, Jauan Jennings all out: 49ers skeleton crew to face Rams
  From the Web › San Francisco Standard
  Mac Jones will make his third start of the season under center
  Share • Oct 1, 2025 at 2:40 PM
  May require subscription
• Brock Purdy, 49ers' top receivers ruled out for Thursday night at Rams
  From the Web › The Mercury News
  Purdy's toe injury flared up after Sunday's loss to Jaguars, while Pearsall suffered a knee injury in the loss.
  Share • Oct 1, 2025 at 2:40 PM
  May require subscription