The 49ers are dealing with yet another injury concern.
Via multiple reporters, running back Christian McCaffrey is sitting out of Monday's practice due to what the club termed "tightness."
The specifics of the tightness or when McCaffrey might get back on the field have not yet been disclosed.
McCaffrey is the latest in a wave of injuries that have affected San Francisco since the start of training camp. At one point last week, the club had 20 players sidelined due to injury.
In addition to McCaffrey, edge rusher Nick Bosa remains out of practice with what the team has called soreness. Bosa has now missed four consecutive practices.
Mike Evans, Christian Kirk, and De'Zhaun Stribling also were not practicing on Monday, according to multiple reporters on the scene.
McCaffrey may be back on the field soon, but the running back missing a practice at all is at least a reason to raise an eyebrow.