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49ers vs. Cardinals recap: Brock Purdy brilliant in 41-22 Week 11 win

Published Nov 16, 2025 at 12:00 PM
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What to Know The San Francisco 49ers (7-4) grabbed a bounce-back win in their Week 11 game against the Arizona Cardinals (3-7) with a dominant 41-22 victory Sunday at State Farm Stadium. Starting quarterback Brock Purdy was stellar in his return from a turf toe injury that kept him out of the 49ers’ last six games, completing 19 of 26 passes for 200 yards with three touchdowns, no interceptions and a 133.5 passer rating. Running back Christian McCaffrey scored three touchdowns — two on the ground and one in the air — finishing with 81 rushing yards on 13 carries and 40 receiving yards on five catches. Tight end George Kittle scored twice and was the 49ers’ leading receiver with Purdy back in action, recording 67 yards on six receptions, including a 30-yard touchdown catch. Read below for all the game highlights, news, analysis and postgame press conferences from State Farm Stadium in Glendale, Ariz.:

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