Robert Saleh's defensive line has lost Williams and star Nick Bosa for the season and is without Yetur Gross-Matos, who was placed on injured reserve.
49ers grades: Mykel Williams’ crushing knee injury should spur trade deadline movement
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49ers injury news: Shanahan on severity of Mykel Williams' torn ACL; Still no Aiyuk; Huff, Pearsall updates
By David Bonilla
Nov 3, 2025
ESPN's Jeremy Fowler was the first to report that San Francisco 49ers head coach Kyle Shanahan's fears from Sunday afternoon were confirmed—rookie defensive end Mykel Williams suffered a torn ACL and will undergo season-ending surgery.
Shanahan spoke with reporters via...
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