The San Francisco 49ers will be without two key offensive starters once again as they take on an excellent Houston Texans defense in Week 8.
5 players out, 3 questionable on 49ers Week 8 injury report
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49ers vs. Texans final injury report: Purdy, Pearsall among 5 ruled out for Sunday
By David Bonilla
Oct 24, 2025
The San Francisco 49ers are preparing for their Week 8 contest against the Houston Texans on Sunday at NRG Stadium in Houston, Texas. Both teams have released their official injury reports, which are provided below.
San Francisco 49ers
Out
C Jake Brendel (hamstring)
DE Yetur...
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