The San Francisco 49ers struggled in their home opener, but they left Week 3 with a win vs. the Arizona Cardinals. Here are the highlights.
49ers vs. Cardinals highlights: San Francisco wins sloppy NFL Week 3 game
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49ers vs. Cardinals in Week 3: How to watch, stream, and listen, plus odds
By Site Staff
Sep 17, 2025
The San Francisco 49ers return to Levi's Stadium for their first home game of the season, taking on the Arizona Cardinals. This matchup marks the 68th all-time meeting between the two teams, with the 49ers leading the series 36-31 and aiming to improve to 21-15 at home against...
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