What's the latest on Christian McCaffrey's injury? Here's what we know.
Will Christian McCaffrey play in Week 1 for 49ers?
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NFL insider says 49ers "aren't overly concerned" about Christian McCaffrey's calf issue
By Marc Adams
Sep 6, 2025
If you heard something that sounded like a giant gasping noise coming from the San Francisco Bay Area on Thursday, it was likely the collective reactions from the 49ers fanbase as news broke that star running back Christian McCaffrey did not practice due to a calf issue. You'll...
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