San Francisco 49ers running back Christian McCaffrey (calf; questionable) is likely to play in Sunday's Week 1 game against the Seattle Seahawks.
Niners RB Christian McCaffrey (calf) likely to play vs. Seahawks
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49ers' Christian McCaffrey plans to play vs. Seahawks: 'I feel great'
By David Bonilla
Sep 5, 2025
San Francisco 49ers running back Christian McCaffrey is listed as "questionable" for Sunday's matchup against the Seattle Seahawks due to a calf injury. Head coach Kyle Shanahan confirmed that McCaffrey did not participate in Friday's practice after being limited on Thursday....
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