San Francisco 49ers star running back Christian McCaffrey is officially questionable for Sunday's season opener against the rival Seattle Seahawks due to a calf injury.
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Niners’ Christian McCaffrey (calf) questionable for Week 1 vs. Seahawks, downplays absence as precaution
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49ers vs. Seahawks final injury report: Christian McCaffrey doesn't practice, questionable for Sunday
By David Bonilla
Sep 5, 2025
The San Francisco 49ers are preparing for their Week 1 contest against the Seattle Seahawks on Sunday at Lumen Field in Seattle, Washington. Both teams have released their official injury reports, which are provided below.
San Francisco 49ers
Doubtful
RB Jordan James...
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