The San Francisco 49ers travel to SoFi Stadium to take on the Los Angeles Chargers in the second game of the 2026 preseason. This matchup marks the 52nd preseason meeting between the two teams. San Francisco looks to improve to 29-23 all-time in the preseason series against the Chargers.
Previous game
The 49ers are coming off a loss at home to the Tennessee Titans. On offense, QB Adrian Martinez completed 16 of 30 passing attempts for 159 yards, while QB Kurtis Rourke completed 12 of 14 attempts for 101 yards. RB Sincere McCormick registered 10 carries for a team-high 38 yards, and RB Patrick Taylor Jr. added a one-yard rushing touchdown. Rookie WR De'Zhaun Stribling led the passing attack with seven receptions for 63 yards, while WR Jordan Watkins added six receptions for 59 yards.
Defensively, the 49ers registered 3.0 sacks and held the Titans to 112 passing yards. The unit was led by LB Nick Martin, who recorded a team-high eight tackles. LB Tatum Bethune added six tackles and 1.0 sack of Titans QB Will Levis, while DL Ogbo Okoronkwo recorded 1.0 sack. DL James Thompson Jr. and LB Larry Worth III split a sack of Levis.
The 49ers Communications staff provided the above breakdown.
Below is everything you need to know to follow the upcoming game.
When does the game start?
Thursday, August 20 at 7:00 p.m. PT
Where is the game being played?
SoFi Stadium in Inglewood, California
Who are the head coaches?
49ers: Kyle Shanahan
Chargers: Jim Harbaugh
Betting Odds
As of August 18, the Chargers are favored by 1.5 points in this game, with an over/under set at 38.5 points, per BetMGM.
What channel is the game on?
49ers Broadcast
Network: KPIX 5 and CW Bay Area
Play-by-Play: Guy Haberman
Color Analyst: Tim Ryan
Sideline Reporter: Vern Glenn
Chargers Broadcast
Network: CBS Los Angeles
Play-by-Play: Noah Eagle
Color Analyst: Dan Fouts
Sideline Reporter: Jaime Maggio
What areas will receive the broadcast?
The broadcast will be viewable in the Bay Area and the Los Angeles area. NFL Network is also scheduled to air the game nationally.
Where can I stream the game?
NFL+ subscribers can stream the game in its entirety. Additionally, Bay Area fans can stream the game through the official 49ers app.
Where can I listen to the radio broadcast?
49ers Radio
Bay Area fans can listen on KGO 810 AM and The Bone 107.7 FM, where Bob Fitzgerald and Keena Turner will call the game.
Jesús Zárate and Carlos Yustis will call the game in Spanish. Fans can listen at 49ers.com/esp.
Chargers Radio
Los Angeles-area fans can listen on KFI AM 640, where Matt "Money" Smith and Daniel Jeremiah will call the game.
Streaming
NFL+ subscribers can listen to the game through that service.
Game discussion
Fans can discuss the game within our Niner Talk forum.
How has this series played out historically?
Preseason Matchups: 51
Preseason Series: 49ers lead series 28-23
First Preseason Meeting: 8/3/68, Chargers win, 30-18, at SD
Last Preseason Meeting: 8/23/25, 49ers win, 30-23, at SF
Current Streak: Won 1
Longest 49ers Win Streak: 8 (9/2/10 - 8/31/17)
Longest Chargers Win Streak: 4 (8/15/81 - 8/18/84)
Most 49ers Points: 41 (8/29/13): 49ers win, 41-6, at SD
Most Chargers Points: 35 (8/18/84): Chargers win, 35-15, at SD
49ers Shutouts: None
Chargers Shutouts: None
SD - San Diego, CA; LA - Los Angeles
Comments